Aspergillus species identification in the clinical setting

S.A. Balajee1*, J. Houbraken2, P.E. Verweij3, S-B. Hong4, T. Yaghuchi5, J. Varga2,6 and R.A. Samson2

1Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, U.S.A., 2CBS Fungal Biodiversity Centre, Utrecht, The Netherlands; 3Department of
Medical Microbiology, Radboud University Nijmegen Medical Center and Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands; 4Korean Agricultural
Culture Collection, Suwon, Korea; 5Medical Mycology Research Center, Chiba University, Chiba, Japan; 6Department of Microbiology, Faculty of Sciences, University of Szeged,
H-6701 Szeged, P.O. Box 533, Hungary

Correspondence: S. Arunmozhi Balajee, fir3@cdc.gov

Abstract: Multiple recent studies have demonstrated the limited utility of morphological methods used singly for species identification of clinically relevant aspergilli. It is
being increasingly recognised that comparative sequence based methods used in conjunction with traditional phenotype based methods can offer better resolution of species
within this genus. Recognising the growing role of molecular methods in species recognition, the recently convened international working group meeting entitled “Aspergillus
Systematics in the Genomic Era” has proposed several recommendations that will be useful in such endeavors. Specific recommendations of this working group include the use
of the ITS regions for inter section level identification and the β-tubulin locus for identification of individual species within the various Aspergillus sections.


Key words: Emericella, molecular phylogeny, pathogenic aspergilli, polyphasic taxonomy, section Aspergillus section Terrei, section Usti.

Untuk download full text klik di sini

Subscribe to receive free email updates:

0 Response to "Aspergillus species identification in the clinical setting"